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Extravascular injection may cause local tissue damage with subsequent necrosis; consequences of intra-arterial injection may vary from transient pain to gangrene of the limb. Any complaint of pain Per the limb warrants stopping the injection.
Clinical studies of Nembutal have not included sufficient numbers of subjects aged 65 and over to determine whether elderly subjects respond differently from younger subjects. Other reported clinical experience has not identified differences Durante responses between the elderly and younger patients.
Premature infants are particularly susceptible to the depressant effects of barbiturates. If barbiturates are used during labor and delivery, resuscitation equipment should be available.
Most reports of clinically significant drug interactions occurring with the barbiturates have involved phenobarbital. However, the application of these patronato to other barbiturates appears valid and warrants serial blood level determinations of the relevant drugs when there are multiple therapies.
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According to AAN guidelines on convulsive status epilepticus, EEG monitoring is required when administering pentobarbital.[2] Clinicians must be aware that pentobarbital is often confused with check here phenobarbital, a different drug with differing dosages and a similar mechanism of action.
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Use of pentobarbital during labor can cause respiratory depression in the newborn. Resuscitation equipment should be ready, especially for premature infants.